Burkholderia cenocepacia J2315, BCAL1057 (hisP)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1057
NCBI Locus Tag	QU43_RS41855
Name	hisP
Replicon	chromosome 1
Genomic location	1144832 - 1145632 (+ strand)

Cross-References

RefSeq	WP_006488736.1
GI	206559444
Entrez	6933718
GI	206559444
INSDC	CAR51360.1
NCBI Locus Tag	QU43_RS41855
NCBI Old Locus Tag	BCAL1057
RefSeq	WP_006488736.1,GeneID
UniParc	UPI00017B91CF
UniProtKB Acc	B4ECZ3
UniProtKB ID	B4ECZ3_BURCJ
UniRef100	UniRef100_A0A088URY4
UniRef50	UniRef50_P02915
UniRef90	UniRef90_Q39I30

Product

Feature Type	CDS
Coding Frame	1
Product Name	histidine ABC transporter ATP-binding protein
Synonyms
Evidence for Translation
Charge (pH 7)	2.38
Kyte-Doolittle Hydrophobicity Value	-0.271
Molecular Weight (kDa)	29420.7
Isoelectric Point (pI)	7.89

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001020 (633 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1057 Search term: hisP Search term: histidine ABC transporter ATP-binding protein

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000352135 ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] E-value: 6.7e-20 Percent Identity: 32.9
Ensembl 97, assembly GRCh38.p12	ENSP00000496956 ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] E-value: 6.7e-20 Percent Identity: 32.9
Ensembl 97, assembly GRCh38.p12	ENSP00000351172 ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] E-value: 6.7e-20 Percent Identity: 32.9
Ensembl 97, assembly GRCh38.p12	ENSP00000392983 ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] E-value: 6.7e-20 Percent Identity: 32.9

References