Burkholderia cenocepacia J2315, BCAL0899 (gloA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0899
NCBI Locus Tag	QU43_RS41045
Name	gloA
Replicon	chromosome 1
Genomic location	978859 - 979242 (+ strand)

Cross-References

RefSeq	WP_006477863.1
GI	206559292
Entrez	6931304
GI	206559292
INSDC	CAR51205.1
NCBI Locus Tag	QU43_RS41045
NCBI Old Locus Tag	BCAL0899
RefSeq	WP_006477863.1,GeneID
UniParc	UPI000052D73F
UniProtKB Acc	B4EBF0
UniProtKB ID	B4EBF0_BURCJ
UniRef100	UniRef100_B1JY69
UniRef50	UniRef50_W6M5E2
UniRef90	UniRef90_A0A095E0Y2

Product

Feature Type	CDS
Coding Frame	1
Product Name	lactoylglutathione lyase
Synonyms
Evidence for Translation
Charge (pH 7)	-3.08
Kyte-Doolittle Hydrophobicity Value	-0.340
Molecular Weight (kDa)	14274.2
Isoelectric Point (pI)	5.63

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 360 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002561 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0899 Search term: gloA Search term: lactoylglutathione lyase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000460634 glyoxalase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:14111] E-value: 5.1e-10 Percent Identity: 30.0
Ensembl 97, assembly GRCh38.p12	ENSP00000301329 glyoxalase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:14111] E-value: 5.1e-10 Percent Identity: 30.0

References