Burkholderia cenocepacia J2315, BCAL0800 (prs)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0800
NCBI Locus TagQU43_RS40555
Name
prs
Replicon chromosome 1
Genomic location 871800 - 872735 (- strand)

Cross-References

RefSeq YP_002229957.1
GI 206559197
Entrez 6931225
GI 206559197
INSDC CAR51108.1
NCBI Locus Tag QU43_RS40555
NCBI Old Locus Tag BCAL0800
RefSeq YP_002229957.1
UniParc UPI00017B90E4
UniProtKB Acc B4EAR3
UniProtKB ID B4EAR3_BURCJ
UniRef100 UniRef100_B4EAR3
UniRef50 UniRef50_Q89DJ1
UniRef90 UniRef90_Q2T1B7

Product

Feature Type CDS
Coding Frame 1
Product Name
ribose-phosphate pyrophosphokinase
Synonyms
Evidence for Translation
Charge (pH 7) -1.67
Kyte-Doolittle Hydrophobicity Value 0.177
Molecular Weight (kDa) 33508.4
Isoelectric Point (pI) 5.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3DAH TRANSFERASE 05/29/08 2.3 A crystal structure of ribose-phosphate pyrophosphokinase from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 2.3 X-RAY DIFFRACTION 97.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 661 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002653 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0800
Search term: prs

Human Homologs

Ensembl 97, assembly GRCh38.p12
phosphoribosyl pyrophosphate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:9465]
E-value: 9.1e-77
Percent Identity: 47.6

References

No references are associated with this feature.