Burkholderia cenocepacia J2315, BCAL0739 (gpmA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0739
NCBI Locus Tag	QU43_RS40250
Name	gpmA
Replicon	chromosome 1
Genomic location	806373 - 807119 (- strand)

Cross-References

RefSeq	WP_006481562.1
GI	206559136
Entrez	6931176
GI	206559136
INSDC	CAR51047.1
NCBI Locus Tag	QU43_RS40250
NCBI Old Locus Tag	BCAL0739
RefSeq	WP_006481562.1,GeneID
UniParc	UPI00017B8EE7
UniProtKB Acc	B4EA64
UniProtKB ID	GPMA_BURCJ
UniRef100	UniRef100_B4EA64
UniRef50	UniRef50_Q39CN6
UniRef90	UniRef90_Q39CN6

Product

Feature Type	CDS
Coding Frame	1
Product Name	phosphoglyceromutase
Synonyms
Evidence for Translation
Charge (pH 7)	-0.59
Kyte-Doolittle Hydrophobicity Value	-0.394
Molecular Weight (kDa)	27938.6
Isoelectric Point (pI)	6.80

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3GP5	ISOMERASE	03/20/09	Crystal structure of phosphoglyceromutase from Burkholderia pseudomallei with 3-phosphoglyceric acid and vanadate	BURKHOLDERIA PSEUDOMALLEI	2.25	X-RAY DIFFRACTION	92.7
3GW8	ISOMERASE	03/31/09	Crystal structure of phosphoglyceromutase from Burkholderia pseudomallei with vanadate and glycerol	BURKHOLDERIA PSEUDOMALLEI	1.93	X-RAY DIFFRACTION	92.7
3EZN	ISOMERASE	10/23/08	Crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710b	BURKHOLDERIA PSEUDOMALLEI 1710B	2.1	X-RAY DIFFRACTION	92.7
3FDZ	ISOMERASE	11/26/08	Crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710b with bound 2,3-diphosphoglyceric acid and 3-phosphoglyceric acid	BURKHOLDERIA PSEUDOMALLEI 1710B	2.25	X-RAY DIFFRACTION	92.7
3GP3	ISOMERASE	03/20/09	Crystal structure of phosphoglyceromutase from Burkholderia pseudomallei with 2-phosphoserine	BURKHOLDERIA PSEUDOMALLEI	1.5	X-RAY DIFFRACTION	92.7
3LNT	ISOMERASE	02/03/10	Crystal structure of phosphoglyceromutase from Burkholderia Pseudomallei 1710B with bound malonic acid	BURKHOLDERIA PSEUDOMALLEI	2.1	X-RAY DIFFRACTION	92.7

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 422 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002703 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0739 Search term: gpmA Search term: phosphoglyceromutase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000359991 phosphoglycerate mutase 1 [Source:HGNC Symbol;Acc:HGNC:8888] E-value: 3.5e-87 Percent Identity: 61.5

References