Burkholderia cenocepacia J2315, BCAL0710 (lipA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0710
NCBI Locus Tag	QU43_RS40110
Name	lipA
Replicon	chromosome 1
Genomic location	771893 - 772885 (+ strand)

Cross-References

RefSeq	WP_006485242.1
GI	206559108
Entrez	6933793
GI	206559108
INSDC	CAR51019.1
NCBI Locus Tag	QU43_RS40110
NCBI Old Locus Tag	BCAL0710
RefSeq	WP_006485242.1,GeneID
UniParc	UPI00017B8EB9
UniProtKB Acc	B4E9R0
UniProtKB ID	B4E9R0_BURCJ
UniRef100	UniRef100_B4E9R0
UniRef50	UniRef50_Q31F42
UniRef90	UniRef90_Q2T1K5

Product

Feature Type	CDS
Coding Frame	1
Product Name	lipoyl synthase
Synonyms
Evidence for Translation
Charge (pH 7)	0.16
Kyte-Doolittle Hydrophobicity Value	-0.392
Molecular Weight (kDa)	36574.5
Isoelectric Point (pI)	7.02

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 495 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002728 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0710 Search term: lipA Search term: lipoyl synthase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000492260 lipoic acid synthetase [Source:HGNC Symbol;Acc:HGNC:16429] E-value: 5.0e-73 Percent Identity: 48.6

References