Burkholderia cenocepacia J2315, BCAL0681 (metH1)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0681
NCBI Locus Tag	QU43_RS39965
Name	metH1
Replicon	chromosome 1
Genomic location	741851 - 744568 (- strand)

Cross-References

RefSeq	WP_006489098.1
GI	206559079
Entrez	6931134
GI	206559079
INSDC	CAR50990.1
NCBI Locus Tag	QU43_RS39965
NCBI Old Locus Tag	BCAL0681
RefSeq	WP_006489098.1,GeneID
UniParc	UPI00017B9189
UniProtKB Acc	B4E9N1
UniProtKB ID	B4E9N1_BURCJ
UniRef100	UniRef100_A0A0D1DCQ8
UniRef50	UniRef50_Q3BV80
UniRef90	UniRef90_B2JKJ4

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative 5-methyltetrahydrofolate--homocysteine methyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-20.51
Kyte-Doolittle Hydrophobicity Value	-0.138
Molecular Weight (kDa)	99873.1
Isoelectric Point (pI)	5.24

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 480 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002757 (647 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0681 Search term: metH1 Search term: putative 5-methyltetrahydrofolate--homocysteine methyltransferase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000355536 5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468] E-value: 9.9e-265 Percent Identity: 53.8

References