Burkholderia cenocepacia J2315, BCAL0666 (bioF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0666
NCBI Locus TagQU43_RS39890
Name
bioF
Replicon chromosome 1
Genomic location 723458 - 724642 (- strand)

Cross-References

RefSeq WP_006483473.1
GI 206559064
Entrez 6933412
GI 206559064
INSDC CAR50975.1
NCBI Locus Tag QU43_RS39890
NCBI Old Locus Tag BCAL0666
RefSeq WP_006483473.1,GeneID
UniParc UPI00017B914C
UniProtKB Acc B4E9L6
UniProtKB ID BIOF_BURCJ
UniRef100 UniRef100_B4E9L6
UniRef50 UniRef50_Q1GZA7
UniRef90 UniRef90_Q0BBD6

Product

Feature Type CDS
Coding Frame 1
Product Name
8-amino-7-oxononanoate synthase
Synonyms
Evidence for Translation
Charge (pH 7) -2.42
Kyte-Doolittle Hydrophobicity Value 0.205
Molecular Weight (kDa) 40991.9
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5VNX TRANSFERASE 05/01/17 Crystal structure of an 8-amino-7-oxononanoate synthase from Burkholderia multivorans with a potential glycine-PLP-Lys242 cyclized intermediate or byproduct BURKHOLDERIA MULTIVORANS (STRAIN ATCC 17616 / 249) 1.65 X-RAY DIFFRACTION 92.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 507 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002772 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0666
Search term: bioF

Human Homologs

Ensembl 97, assembly GRCh38.p12
5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397]
E-value: 2.2e-43
Percent Identity: 34.8
Ensembl 97, assembly GRCh38.p12
5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397]
E-value: 2.2e-43
Percent Identity: 34.8
Ensembl 97, assembly GRCh38.p12
5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397]
E-value: 2.2e-43
Percent Identity: 34.8

References

No references are associated with this feature.