Burkholderia cenocepacia J2315, BCAL0603 (puuC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0603
NCBI Locus TagQU43_RS39570
Name
puuC
Replicon chromosome 1
Genomic location 657911 - 659401 (+ strand)

Cross-References

RefSeq WP_006488053.1
GI 206559003
Entrez 6931070
GI 206559003
INSDC CAR50912.1
NCBI Locus Tag QU43_RS39570
NCBI Old Locus Tag BCAL0603
RefSeq WP_006488053.1,GeneID
UniParc UPI00017B908F
UniProtKB Acc B4E926
UniProtKB ID B4E926_BURCJ
UniRef100 UniRef100_B4E926
UniRef50 UniRef50_B8CT61
UniRef90 UniRef90_A4JIG4

Product

Feature Type CDS
Coding Frame 1
Product Name
gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -8.03
Kyte-Doolittle Hydrophobicity Value 0.065
Molecular Weight (kDa) 52822.8
Isoelectric Point (pI) 5.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4LIH OXIDOREDUCTASE 07/02/13 The crystal structure of Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase from Burkholderia cenocepacia J2315 BURKHOLDERIA CENOCEPACIA 1.85 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 599 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002822 (628 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0603
Search term: puuC

Human Homologs

Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 2 family member [Source:HGNC Symbol;Acc:HGNC:404]
E-value: 5.3e-111
Percent Identity: 46.0

References

No references are associated with this feature.