Burkholderia cenocepacia J2315, BCAL0522 (fliI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0522
NCBI Locus TagQU43_RS39175
Name
fliI
Replicon chromosome 1
Genomic location 574411 - 575916 (- strand)

Cross-References

RefSeq YP_002229683.1
GI 206558923
Entrez 6933590
GI 206558923
NCBI Locus Tag QU43_RS39175
NCBI Old Locus Tag BCAL0522
RefSeq YP_002229683.1
UniProtKB Acc B4E813
UniProtKB ID B4E813_BURCJ

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellum-specific ATP synthase FliI
Synonyms
Evidence for Translation
Charge (pH 7) -5.47
Kyte-Doolittle Hydrophobicity Value 0.039
Molecular Weight (kDa) 52981.9
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database BGD
Category Flagella
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Homo sapiens
Notes fliI mutation has reduced invasion of A549 cell monolayers
Reference 11895941
Source 2
Database VFDB : VF0430
Category Flagella
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 666 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002892 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0522
Search term: fliI

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP synthase F1 subunit beta [Source:HGNC Symbol;Acc:HGNC:830]
E-value: 7.9e-38
Percent Identity: 30.3

References

No references are associated with this feature.