Burkholderia cenocepacia J2315, BCAL0474

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0474
NCBI Locus Tag	QU43_RS38935
Name
Replicon	chromosome 1
Genomic location	524381 - 525013 (+ strand)

Cross-References

RefSeq	WP_006482565.1
GI	206558876
Entrez	6930992
GI	206558876
INSDC	CAR50785.1
NCBI Locus Tag	QU43_RS38935
NCBI Old Locus Tag	BCAL0474
RefSeq	WP_006482565.1,GeneID
UniParc	UPI00017B8F79
UniProtKB Acc	B4E7W6
UniProtKB ID	B4E7W6_BURCJ
UniRef100	UniRef100_B4E7W6
UniRef50	UniRef50_Q89SC0
UniRef90	UniRef90_A9AC61

Product

Feature Type	CDS
Coding Frame	1
Product Name	hypothetical protein
Synonyms
Evidence for Translation
Charge (pH 7)	-8.25
Kyte-Doolittle Hydrophobicity Value	-0.167
Molecular Weight (kDa)	23221.2
Isoelectric Point (pI)	4.69

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4NJK	LYASE	11/10/13	Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 7-carboxy-7-deazaguanine, and Mg2+	BURKHOLDERIA MULTIVORANS	1.911	X-RAY DIFFRACTION	97.6
4NJI	LYASE	11/10/13	Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Mg2+	BURKHOLDERIA MULTIVORANS	2.197	X-RAY DIFFRACTION	97.6
4NJH	LYASE	11/10/13	Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxy-5,6,7,8-tetrahydropterin	BURKHOLDERIA MULTIVORANS	1.898	X-RAY DIFFRACTION	97.6
4NJG	LYASE	11/10/13	Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxypterin	BURKHOLDERIA MULTIVORANS	2.598	X-RAY DIFFRACTION	97.6
4NJJ	LYASE	11/10/13	Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Manganese(II)	BURKHOLDERIA MULTIVORANS	2.7	X-RAY DIFFRACTION	97.6

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 399 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002946 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0474

Human Homologs

References