Burkholderia cenocepacia J2315, BCAL0344 (tssE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0344
NCBI Locus TagQU43_RS38255
Name
tssE
Synonym: bcsI
Replicon chromosome 1
Genomic location 369563 - 370048 (+ strand)
CommentPart of the T6SS gene cluster

Cross-References

RefSeq WP_006477092.1
GI 206558750
Entrez 6930889
GI 206558750
INSDC CAR50654.1
NCBI Locus Tag QU43_RS38255
NCBI Old Locus Tag BCAL0344
RefSeq WP_006477092.1,GeneID
UniParc UPI00003A7E99
UniProtKB Acc B4E6R6
UniProtKB ID B4E6R6_BURCJ
UniRef100 UniRef100_B1JUP0
UniRef50 UniRef50_M4UL80
UniRef90 UniRef90_Q2SUD1

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system protein TssE
Product Name Confidence: Class 1
Synonyms putative type VI secretion system protein TssE
Evidence for Translation
Charge (pH 7) -3.87
Kyte-Doolittle Hydrophobicity Value -0.189
Molecular Weight (kDa) 18128.4
Isoelectric Point (pI) 5.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 69 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000369 (643 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0344
Search term: tssE

Human Homologs

References

A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149