Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAL1934
|
NCBI Locus Tag | QU43_RS46215 |
Name |
arnA2
|
Replicon | chromosome 1 |
Genomic location | 2133771 - 2134826 (+ strand) |
Comment | In PMID:27597847: arnT, arnB, arnC, arnA1, arnA2, and BCAL1935 located in the arn gene cluster harbored significantly low frequencies of transposon insertions (TraDIS). They were therefore categorized as essential by the authors. |
RefSeq | YP_002231062.1 |
GI | 206560298 |
Entrez | 6932123 |
GI | 206560298 |
INSDC | CAR52235.1 |
NCBI Locus Tag | QU43_RS46215 |
NCBI Old Locus Tag | BCAL1934 |
RefSeq | YP_002231062.1 |
UniParc | UPI00002D76A4 |
UniProtKB Acc | B4EB20 |
UniProtKB ID | B4EB20_BURCJ |
UniRef100 | UniRef100_A0A071MNK8 |
UniRef50 | UniRef50_Q8XZS6 |
UniRef90 | UniRef90_A9AJX2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
putative UDP-4′-keto-5′-carboxypentose decarboxylase
|
Synonyms |
NAD-dependent epimerase/dehydratase family protein |
Evidence for Translation | |
Charge (pH 7) | -4.92 |
Kyte-Doolittle Hydrophobicity Value | -0.259 |
Molecular Weight (kDa) | 39451.7 |
Isoelectric Point (pI) | 6.05 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3SLG | TRANSFERASE | 06/24/11 | Crystal structure of PbgP3 protein from Burkholderia pseudomallei | BURKHOLDERIA PSEUDOMALLEI | 2.1 | X-RAY DIFFRACTION | 95.4 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 525 genera
|
Burkholderia Ortholog Group |
BG001696 (652 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAL1934
Search term: arnA2
|
A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability.
Ortega XP, Cardona ST, Brown AR, Loutet SA, Flannagan RS, Campopiano DJ, Govan JR, Valvano MA
J Bacteriol 2007 May;189(9):3639-44
PubMed ID: 17337576
|
PubMed ID: 22742453
|
Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis.
Williams GJ, Breazeale SD, Raetz CR, Naismith JH
J Biol Chem 2005 Jun 17;280(24):23000-8
PubMed ID: 15809294
|
Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS.
Wong YC, Abd El Ghany M, Naeem R, Lee KW, Tan YC, Pain A, Nathan S
Front Microbiol 2016;7:1288
PubMed ID: 27597847
|