Burkholderia cenocepacia J2315, BCAL0226 (rpoB)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0226
NCBI Locus Tag	QU43_RS37665
Name	rpoB
Replicon	chromosome 1
Genomic location	259249 - 263355 (+ strand)

Cross-References

RefSeq	WP_012492293.1
GI	206558633
Entrez	6934067
GI	206558633
INSDC	CAR50537.1
NCBI Locus Tag	QU43_RS37665
NCBI Old Locus Tag	BCAL0226
RefSeq	WP_012492293.1,GeneID
UniParc	UPI00017B8FF5
UniProtKB Acc	B4E5B2
UniProtKB ID	RPOB_BURCJ
UniRef100	UniRef100_B4E5B2
UniRef50	UniRef50_O52271
UniRef90	UniRef90_A3MRU5

Product

Feature Type	CDS
Coding Frame	1
Product Name	DNA-directed RNA polymerase subunit beta
Synonyms
Evidence for Translation
Charge (pH 7)	-26.03
Kyte-Doolittle Hydrophobicity Value	-0.345
Molecular Weight (kDa)	153240.4
Isoelectric Point (pI)	5.38

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 667 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000250 (653 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0226 Search term: rpoB Search term: DNA-directed RNA polymerase subunit beta

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000445721 RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] E-value: 3.8e-26 Percent Identity: 30.2
Ensembl 97, assembly GRCh38.p12	ENSP00000228347 RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] E-value: 3.8e-26 Percent Identity: 30.2

References