Burkholderia cenocepacia J2315, BCAL0204 (pyrE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0204
NCBI Locus TagQU43_RS37505
Name
pyrE
Replicon chromosome 1
Genomic location 228292 - 228978 (- strand)

Cross-References

RefSeq WP_006482887.1
GI 206558610
Entrez 6930829
GI 206558610
INSDC CAR50514.1
NCBI Locus Tag QU43_RS37505
NCBI Old Locus Tag BCAL0204
RefSeq WP_006482887.1,GeneID
UniParc UPI00017B8FA3
UniProtKB Acc B4E589
UniProtKB ID B4E589_BURCJ
UniRef100 UniRef100_A0A071ME06
UniRef50 UniRef50_G8AJG7
UniRef90 UniRef90_C5A900

Product

Feature Type CDS
Coding Frame 1
Product Name
orotate phosphoribosyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -1.38
Kyte-Doolittle Hydrophobicity Value -0.118
Molecular Weight (kDa) 25496.9
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4OHC TRANSFERASE 01/17/14 Crystal structure of orotate phosphoribosyltransferase (OPRTase) from Burkholderia cenocepacia BURKHOLDERIA CENOCEPACIA 1.85 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 291 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000227 (656 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0204
Search term: pyrE

Human Homologs

References

No references are associated with this feature.