Burkholderia cenocepacia J2315, BCAL0204 (pyrE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004588 orotate phosphoribosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01208
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006221 pyrimidine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01208
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009116 nucleoside metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00156
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00983 Drug metabolism - other enzymes InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc UMP biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd06223 PRTases_typeI IPR000836 Phosphoribosyltransferase domain 72 184 1.8392E-15
Gene3D G3DSA:3.40.50.2020 1 228 9.9E-73
TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase IPR004467 Orotate phosphoribosyl transferase domain 16 184 1.4E-32
SUPERFAMILY SSF53271 IPR029057 Phosphoribosyltransferase-like 15 220 4.44E-44
Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. IPR023031 Orotate phosphoribosyltransferase 1 228 28.515
Pfam PF00156 Phosphoribosyl transferase domain IPR000836 Phosphoribosyltransferase domain 56 160 1.5E-11

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.