Burkholderia mallei ATCC 23344, BMAA1529 (bprA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1529
Name
bprA
Replicon chromosome 2
Genomic location 1658224 - 1658514 (- strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.

Cross-References

RefSeq YP_106119.1
GI 53716476
NCBI Locus Tag BMAA1529
RefSeq YP_106119.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
regulatory protein BprA (T3SS-3)
Product Name Confidence: Class 2
Synonyms DNA-binding protein BprA
Evidence for Translation
Charge (pH 7) 6.47
Kyte-Doolittle Hydrophobicity Value -0.896
Molecular Weight (kDa) 10910.2
Isoelectric Point (pI) 10.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019831 (366 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1529
Search term: bprA

Human Homologs

References

Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152