Burkholderia cenocepacia AU 1054, BCEN_RS14550

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0030976 thiamine pyrophosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52518 IPR029061 Thiamin diphosphate-binding fold 376 550 2.6E-56
CDD cd07035 TPP_PYR_POX_like 17 172 6.37541E-46
Gene3D G3DSA:3.40.50.970 4 191 3.0E-60
Pfam PF00205 Thiamine pyrophosphate enzyme, central domain IPR012000 Thiamine pyrophosphate enzyme, central domain 200 333 5.6E-28
ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. IPR000399 TPP-binding enzyme, conserved site 431 450 -
SUPERFAMILY SSF52518 IPR029061 Thiamin diphosphate-binding fold 7 186 1.77E-51
Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding 395 541 2.0E-42
Gene3D G3DSA:3.40.50.970 370 565 2.6E-55
CDD cd00568 TPP_enzymes 377 543 9.98327E-67
Gene3D G3DSA:3.40.50.1220 193 363 1.6E-35
Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 13 181 3.1E-52
SUPERFAMILY SSF52467 IPR029035 DHS-like NAD/FAD-binding domain superfamily 165 365 3.74E-38

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.