Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS34775 (ptwK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest
Locus Tag
BURCENK562V_RS34775
NCBI Old Locus TagBURCENK562V_C0097
Name
ptwK
Replicon ctg7180000002935
Genomic location 62162 - 62908 (- strand)
CommentThis gene is part of the B. cenocepacia K56-2 plasmid-encoded ptw type IV secretion cluster.

Cross-References

RefSeq WP_012493842.1
GI 501470397
GI 501470397
NCBI Locus Tag BURCENK562V_RS34775
NCBI Old Locus Tag BURCENK562V_C0097
RefSeq WP_012493842.1

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Charge (pH 7) -4.53
Kyte-Doolittle Hydrophobicity Value -0.127
Molecular Weight (kDa) 26529.6
Isoelectric Point (pI) 4.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG007429 (37 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: ptwK

Human Homologs

References

A Functional oriT in the Ptw Plasmid of Burkholderia cenocepacia Can Be Recognized by the R388 Relaxase TrwC.
Fernández-González E, Bakioui S, Gomes MC, O'Callaghan D, Vergunst AC, Sangari FJ, Llosa M
Front Mol Biosci 2016;3:16
PubMed ID: 27200362
Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538